Immunoprofiling for advanced biomarker discovery

Sengenics at a glance

Sengenics is a proteomics company with a unique technology used to produce full-length, correctly folded, and functional proteins. The technology is leveraged to support pharma and academic research to advance precision medi­cine through an increased understanding of the autoimmune response in humans. Sengenics is currently focused on measurement of autoanti­bodies for applications in autoimmune diseases, oncology, neurological conditions, and infectious disease.

Year acquired

2019

Sector

Life science

Employees

42

Investment themes

Changing Demographics

Key developments in 2022

2nd half of 2022 was characterized by the appointment of a high caliber CEO, Jerry Williamson. Sengenics continued to serve customers globally, with an increased focus on large pharma customers, who deploy the KREX technology over various use cases and therapeutic indications. Earlier in the year, the com­pany launched the Pan-Autoimmune product, a new protein array service.

The challenges we face

We currently suffer from ineffective medication due to limited understanding of the biology of diseases. The shift from the "one size fits all" approach to precision medicine is a colossal challenge for science. Development of autoantibody biomarker signatures enable improved understanding of human biology and can optimize the development of safer and higher efficacy drugs, hence enabling healthcare to become more personalized and for the right treatment to be delivered to the right patient at the appropriate time.

0%

of patients receive no benefit from treatment with the top 10 best-selling drugs in the world.

0%

of OECD GDP is spent on healthcare.

How does Sengencis help?

Reality today

We do not understand the biology of many leading diseases and lack appropriate biomarkers, prevent­ing us from developing effective medication and delivering preci­sion treatment.

Sengencis approach

Sengenics proteomics technology enables biological response re­search at unrivalled sensitivity and specificity, helping develop more targeted, effective, and efficient diagnostics and therapies.

Aspirational future

Deeper understanding of human biology and disease allows us to develop and deliver the most effective diagnostics and treatments for patients.

Who is impacted?

Researchers are impacted directly through more effective tools to understand human biology. Patients are impacted indirectly through break­throughs in treatments.

What are the impact considerations?

Additionality

Sengenics unique technology and collaborative partnerships with top biopharma companies is driving forward precise, cost-effective research that would not otherwise be possible.

Risks

Sengenics impact depends in part on how its customers in biopharma choose to use its tools. Product quality is also fundamentally important, enabling reproducibility in research and precise, safe innovation in therapies.







SDG alignments

SDG 3

KPI reporting

Data points generated

2022:
-0%
2m
2020:
9m
2020:
6m

Accumulated no. of publications

2022:
+0%
40
2021:
31
2020:
23

Number of samples profiled

2022:
+0%
4 833
2021:
4 090
2020:
2 005